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居酒屋で10杯飲んでも大して酔わないのに、
→ “Even though I don't really get drunk even after drinking 10 cups at an izakaya,”
居酒屋 izakaya = pub / bar (n.)
居 i = to live / reside
酒 sake = alcohol / wine
屋 ya = shop / building
で de = at / in (location particle)
10杯 jū¹-hai = ten cups (numeral + counter)
十 jū¹ = ten
杯 hai = cup (counter for drinks)
飲んでも nondemo = even if drink (v. te-form + conditional)
飲 nomu = to drink
ん = colloquial contraction of 'mu'
でも demo = even if / although
大して taishite = not much / hardly (adverb)
酔わない yowanai = do not get drunk (v. nai negative form)
酔 yoi = to be drunk
ない nai = not (negative copula)
のに、 no ni = even though / despite the fact that (conjunction)